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MedImmune, Infinity Sign Cancer Pact

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By: Tim Wright

Editor-in-Chief, Contract Pharma

MedImmune and Infinity Pharmaceuticals have entered into an agreement to jointly develop and commercialize novel small molecule cancer drugs targeting Heat Shock Protein 90 (Hsp90) and the Hedgehog cell-signaling pathway. In preclinical studies, Hsp90 and the Hedgehog pathway appear to be implicated in the growth and survival of a broad range of blood-related and solid tumor types. IPI-504, the most advanced of the drug candidates included in the agreement, is an Hsp90 inhibitor that has thus fa...

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